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KMID : 0032220150270040389
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Annals of Dermatology
2015 Volume.27 No. 4 p.389 ~ p.393
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Patch Testing with Dental Screening Series in Oral Disease
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Kim Tae-Wook
Kim Woo-Il
Mun Je-Ho
Song Margaret
Kim Hoon-Soo
Kim Byung-Soo
Kim Moon-Bum
Ko Hyun-Chang
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Abstract
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Background: The oral mucosa is constantly exposed to several irritants and allergens including dental materials, but the role of contact allergy in oral disease is obscure.
Objective: To analyze positive patch test results in patients with oral diseases and evaluate the clinical relevance of oral diseases with contact allergy to dental materials.
Methods: We retrospectively analyzed patch test results with dental screening series in 44 patients with oral disease from 2004∼2011.
Results: Oral diseases included oral lichen planus (54.5%), cheilitis (27.3%), burning mouth syndrome (9.1%), and others (9.1%). Thirty-one of 44 patients (70.5%) had positive reactions to one or more allergens. The most commonly detected allergens were gold sodium thiosulfate (25.0%) and nickel sulfate (25.0%), followed by potassium dichromate (22.7%), cobalt (15.9%), palladium (6.8%), mercury (4.5%), copper (4.5%), and methylhydroquinone (4.5%). Six of 24 patients with oral lichen planus had a symptom in areas adjacent to dental materials and positive patch test reactions to allergens contained in the suspected dental materials.
Conclusion: Patch tests with dental screening series are worth considering for oral diseases, especially for oral lichen planus. (Ann Dermatol 27(4) 389∼393, 2015)
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KEYWORD
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Dental materials, Dental screening series, Oral disease, Patch tests
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